Biphasic model of cartilage

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August undefined, 2024

WebFeb 1, 1980 · We also concluded that 1) a nonlinearly permeable biphasic model, where the permeability function is given by an experimentally determined empirical law: k = A(p) exp [α(p)e], can be used to describe more accurately the rheological properties of articular cartilage, and 2) the frictional drag of relative motion is the most important factor ... WebThe accumulation of MMPs in osteoarthritic cartilage may have a role in the biphasic progression of OA-related pain. Temporal association of changes in ECS and MMPs expression shows a potential therapeutic approach that utilizes the concept of combining indirect ECS-mediated MMP inhibition and ECS modulation of pain transduction.

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http://web.mit.edu/cortiz/www/3.052/3.052CourseReader/27_BiomechanicsofCartilage.pdf WebFrom the experimental results and the biphasic poroviscoelastic theory, we found that frictional drag associated with interstitial fluid flow and fluid pressurization are the dominant mechanisms of load support in the intact specimens, i.e. the flow-dependent mechanisms alone were sufficient to describe normal articular cartilage compressive ... simple asset tracking software

The biphasic poroviscoelastic behavior of articular cartilage: …

WebFeb 1, 2008 · Abstract. A material model of articular cartilage is formulated, and fundamental problems are analyzed. The soft tissue is assumed to comprise two phases: solid and fluid. The biphasic theory proposed by Spilker and Suh (1990) to deal with such materials is reviewed, and some new additional analyses are carried out on the basis of … WebFeb 1, 2008 · Abstract. A material model of articular cartilage is formulated, and fundamental problems are analyzed. The soft tissue is assumed to comprise two phases: … WebApr 14, 2024 · There are several constitutive material models in the literature that can characterize cartilage mechanics in different loading scenarios. Briefly, traditional … ravenwood legacy sims 4

Biomechanics and Modeling of Skeletal Soft Tissues

A cross-validation of the biphasic poroviscoelastic model …

WebCartilage is a multi-phase material composed of fluid and electrolytes (68-85% by wet weight), proteoglycans (5-10% by wet weight), chondrocytes, collagen fibres and other … WebOct 15, 2012 · as the biphasic mechanics of cartilage, can be solved by FEBio using the biphasic material model embedded within the code. A finite element contact implementa-tion for biphasic materials is available in the code. This implementation is able to accommodate finite deforma-tion and large sliding.11 The comparison between different … simple asset purchase agreementWebIt seems that a mechanobiological process drives the remodeling of newborn collagen fibrils with maturation. Therefore, the goal of the present study was to develop a collagen fibril remodeling algorithm that describes the unique collagen fibril organization in a 3D knee model. Method: A fibril-reinforced, biphasic cartilage model was used with ... simple assault in michigan

"WebApr 1, 2024 · This biphasic theory models AC as composite materials consisting of a solid phase (solid like components of the cartilage, proteoglycans, collagen, cells and lipids … " - Biphasic model of cartilage

Biphasic model of cartilage

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WebApr 24, 2024 · The relative scarcity of 3-D constitutive models of cartilage speaks to the challenges of capturing the tissue’s complex behavior in a computation model. Existing 3-D, large-strain FE models of articular cartilage use single-phase (e.g., [31, 87, 88]), biphasic, and multi-phasic models, some at considerable computational cost. WebNational Center for Biotechnology Information

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WebMay 30, 2014 · The cartilage layer is an inhomogeneous fibre-reinforced structure. 4,15,16 Previous studies using models of cylindrical cartilage sections have demonstrated that the constitutive relationship proposed by Ateshian’s group, in which the tensile and compressive behaviour are different, captures the mechanical performance of the tissue more ... WebApr 14, 2024 · There are several constitutive material models in the literature that can characterize cartilage mechanics in different loading scenarios. Briefly, traditional poroelastic and biphasic models can distinguish between solid and fluid phases [32, 48]. When combined with anisotropic properties of the solid matrix, these models can also …

WebThe content of glycosaminoglycan in intervertebral soft tissues and the permeability of cartilage endplates are two critical factors that affect the fluid-dependent viscoelastic responses of intervertebral discs. ... Four biphasic swelling-based finite element models are developed and quantitatively validated. Four quasi-static test protocols ... WebA linear viscoelastic biphasic model for soft tissues based on the Theory of Porous Media. Berichte aus dem Institut für Mechanik (Bauwesen), Nr. 99-II-3, Universität Stuttgart, Stuttgart, 1999. ... S. Finite clement formulation of biphasic poroviscoelastic model of articular cartilage. J. biomech. Engng, 120, 195–201, 1998. CrossRef Google ...

WebOct 1, 1998 · The biphasic model was used in its most basic formulation, namely under the assumption of small strains, tissue homogeneity, isotropy, and constant permeability. ... the role of interstitial fluid pressurization in the contact of biphasic cartilage layers under near-physiologic conditions was investigated (Ateshian et al., 1994; ... WebFor instance, biphasic cartilage-ceramic constructs showed important improvement of regeneration in osteochondral defects in sheep . ... Two-Year Evaluation of Osteochondral Repair with a Novel Biphasic Graft Saturated in Bone Marrow in an Equine Model. Cartilage 2024, 8, 406–416.

WebApr 14, 2024 · 5 Using Models to Investigate Pathways to Cartilage Failure. Synovial joint lubrication is one of the key roles of articular cartilage. Synovial joints can experience very small frictional force, with initial friction coefficient ranging from 0.005 to 0.02, while bearing extremely large mechanical stress [ 41, 42 ].

simple assets worksheetWebApr 1, 2001 · The biphasic poroviscoelastic (BPVE) model is a mathematical model for articular cartilage, which describes the apparent viscoelasticity exhibited by the tissue … simple assistive technologyWebJun 1, 1999 · Cartilage mechanical function relies on a composite structure of a collagen fibrillar network entrapping a proteoglycan matrix. Previous biphasic or poroelastic … simple assim lyricsWebCartilage tissue engineering is emerging as a promising treatment for osteoarthritis, and the field has progressed toward utilizing large animal models for proof of concept and … simple assets to invest inWebApr 1, 2024 · This biphasic theory models AC as composite materials consisting of a solid phase (solid like components of the cartilage, proteoglycans, collagen, cells and lipids … simple asset trackingWebAug 1, 2012 · Mechanical behavior of cartilage is then described by the biphasic or continuous poro-elastic model that describes the mechanical interactions of the different phases (Donzelli & Spilker, 1998). From the … simpleassureWebMar 17, 2024 · (3) Compared with hyperelastic model, the biphasic models may reflect the mechanical characteristics of cartilage thoroughly 31,32,33. Thus, the relaxation or creep experiments need to be ... simple assignment ideas