Tīmeklis2024. gada 31. marts · Other FAK- and Src-interacting proteins, like the actin regulator Eps8, are also involved in this spatial localisation of active Src (Schoenherr et al., 2014). Since Ambra1 is a recognised autophagy regulator, we addressed whether it was required for the trafficking of Src to autophagosomes in FAK-deficient cells. TīmeklisXavier Coumoul, professeur des universités en biochimie et toxicologie à l’université Paris Descartes, s’intéresse depuis plus de 10 ans au mécanisme cellulaire et moléculaire d’action des polluants environnementaux et utilise de nombreux modèles d’étude (cellules, nématodes, souris, études cliniques) pour caractériser le rôle d’un …
Clinical relevance of lysyl oxidase-like 2 and functional …
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Tīmeklis2006. gada 1. okt. · Integrin-stimulated FAK phosphorylation at Y397 creates a high-affinity binding site for the Src-homology 2 (SH2) domain of SFKs. The binding of … Tīmeklis2016. gada 26. apr. · 磷酸化的 FAK与 Src形成复合体,可以激活 或抑制多条下游通路, 包括 PI3K/Akt、R IP、p53 RAS2Erk等,起始肿瘤发生或诱导细胞凋亡。 Wu等 shRNA … Tīmeklis摘 要: 粘附斑激酶(focal adhesion kinase,FAK)是一类胞质非受体蛋白酪氨酸激酶.属于蛋白酪氨酸激酶(protein tyro— sine kinase)超家族,因而也称为PTK 11。. … creality cr-6 se cura settings