Sialic acid acetylesterase
WebJul 8, 2010 · Sialic acid acetylesterase (SIAE) is an enzyme that negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of … WebThis cytosolic sialic acid-specific O-acetylesterase appears to be involved in the "recycling" of O-acetylated sialic acid molecules. Thus, esterase D may be the first nonspecific …
Sialic acid acetylesterase
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WebSialic acid acetylesterase (SIAE) is an enzyme that produces 9-O acetylated sialic acid e.g. in mammals. It down-regulates B lymphocyte antigen receptor signaling (involving CD22 ), … WebJ:37624 Butor C, et al., Structural, immunological, and biosynthetic studies of a sialic acid-specific O-acetylesterase from rat liver. J Biol Chem. 1993 May 15;268(14):10207-13. …
WebEnter the email address you signed up with and we'll email you a reset link. WebNCBI Full Gene Name sialic acid acetylesterase; NCBI Gene Aliases AIS6, CSE-C, CSEC, LSE, YSG2; Clonality Monoclonal; Specifications/Features Available conjugates: ...
WebIntroduction. Carbohydrate esterases catalyze the de-O or de-N-acylation of substituted saccharides. Since an ester = acid + alcohol, we consider two classes of substrates for … WebMar 29, 2024 · Ursini G, Punzi G, Langworthy BW, Chen Q, Xia K, Cornea EA, Goldman BD, Styner MA, Knickmeyer RC, Gilmore JH, Weinberger DR. Placental genomic risk scores …
WebThe crystal structure of NA complexed with sialic acid, which is itself a weak inhibitor of influenza NA with a K i ≈ 1 mM, revealed sialic acid in a strained conformation with its …
The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction ... "High performance liquid chromatography of enzymes of sialic acid metabolism". Hoppe-Seyler's Z. Physiol. Chem. 363: 1039–1040. This page was last edited on 16 August 2024, at 15:45 (UTC). Text is available under the Creative … See more The enzyme sialate O-acetylesterase (EC 3.1.1.53) catalyzes the reaction N-acetyl-O-acetylneuraminate + H2O = N-acetylneuraminate + acetate In human it is encoded by the SIAE gene located on See more The SIAE gene contains 15 exons and expresses a protein that is approximately 56 kDa in size. It is known to be expressed in the adult See more SIAE activity negatively regulates B lymphocyte antigen receptor signalling and is required for the maintenance of immunological tolerance. It down-regulates B lymphocyte antigen receptor signaling (involving CD22), and is required for See more Genetic defects in SIAE have been associated with multiple autoimmune diseases. Loss of function mutations in SIAE are much more frequently found in humans with See more how did russia effect latviaWebAmong coronaviruses, several members are able to interact with sialic acids. For bovine coronavirus (BCoV) and related viruses, binding to cell surface components containing N-acetyl-9- O-acetylneuraminic acid is essential for initiation of an infection. These viruses resemble influenza C viruses because they share not only the receptor determinant, but … how many spanning trees are possibleWebEsterases and autoimmunity: the sialic acid acetylesterase pathway and the regulation of peripheral B cell tolerance Shiv Pillai, Annaiah Cariappa and Stephan P. Pirnie Cancer … how many spanish speakers in spainWebRecombinant Human Sialate O-Acetylesterase is produced by our Mammalian expression system and the target gene encoding Ile24-Lys523 is expressed with a 6His tag at the C ... how did russia developWebMar 5, 2024 · This gene encodes an enzyme which removes 9-O-acetylation modifications from sialic acids. Mutations in this gene are associated with susceptibility to autoimmune … how did russia get the bombWebDocument: Group 2 coronaviruses encode an accessory envelope glycoprotein species, the hemagglutinin esterase (HE), which possesses sialate-O-acetylesterase activity and … how did russia interfere with the uk electionhttp://www.cazy.org/Carbohydrate-Esterases how did russia expand